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Чайник электрический Midea MK 8033


1750 RUR
MK 8033 Midea

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Чайник электрический Midea MK-8033


Объем (л): 1.7 Мощность (кВт): 2.2 Цвет: нержавеющая сталь Страна-производитель: Китай

1190 RUR
MK-8033 Midea

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Midea MK-8033

Подвесная люстра Lussole GRLSP-8033


9801.5 RUR
GRLSP-8033 Lussole

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Сумка 15.6 RivaCase 8033 Black


1537 RUR
8033 RivaCase

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Подвесная люстра Lussole LSP-8033


8521.5 RUR
LSP-8033 Lussole

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Электрочайник Midea MK-8033 серебристый


Наличие фильтра в носике способствует получению вкусного и ароматного напитка без примесей накипи: в вашу кружку будет литься чистая вода без частичек накипи. Для удобства пользования за ручкой предусмотрена шкала уровня воды, позволяющая следить за количеством жидкости в чайнике наряду с соответствующим индикатором.

1860 RUR
Midea

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Раковина Scarabeo Gaia 8033 Белая


Раковина Scarabeo Gaia.

29630 RUR
Gaia 8033 Белая Scarabeo

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Весы кухонные Vitek VT-8033(W)


840 RUR
VT-8033(W) Vitek

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RIVACASE 8033 для ноутбука 15.6" (черный)


Сумка для ноутбука Riva 8033 15.6", выполненная из водопрочного нейлона, отлично подойдет для безопасной переноски 15,6-дюймового ноутбука и сопутствующих аксессуаров. Сумка Riva 8033 15.6" оборудована утолщенными стенками и имеет боковые усиления, что придает ей надежность в условиях городского транспорта. Для удобства переноски модель Riva 8033 15.6" оснащена наплечным ремнем и эргономичной ручкой.

950 RUR
RIVACASE

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MK-8033 | C25H21N5O3S - PubChem

MK-8033. 1001917-37-8. 3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-N-(2-pyridinylmethyl)-5H-benzo[4,5]cyclohepta[1,2-b]pyridine-7-methanesulfonamide. UNII-350H6PBQ5Q. MK8033. More... Molecular Weight: 471.5 g/mol. Dates: Modify: 2020-07-12. Create: 2010-04-26. Contents. 1 Structures Expand this section. 2 Names and Identifiers Expand this section. 3 Chemical and Physical Properties Expand this section ...

MK-8033 | c-Met/HGFR Inhibitor | MedChemExpress

MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer. For research use only. We do not sell to patients. MK-8033 Chemical Structure

First-in-human phase I dose escalation study of MK-8033 in ...

MK-8033 is a small-molecule inhibitor of c-Met that binds preferentially to the activated conformation, and has demonstrated anti-tumor activity in preclinical models. This first-in-human trial was performed to establish the safety and maximum tolerated dose (MTD), as well as preliminary pharmacokinetics (PK) and clinical activity. Methods Forty-seven patients were enrolled in three parts. The ...

MK 8033 - AdisInsight

MK 8033, a small molecule, selective proto-oncogene protein c-met/RON protein inhibitor, is under development by Merck for the treatment of cancer [1] .

MK-8033 - Creative Enzymes

MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre-and post-treatment biopsies to evaluate for relevant molecular signatures.

MK-8033 • Focus Bioscience

MK8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.

MK-8033 | CAS#1001917-37-8 | cMet Inhibitor | MedKoo ...

MK-8033 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote ...

MK-8033 - MedChem Express

MK-8033 - 50 mg. Add to favourites. Data sheet: View or download; MSDS: View or download; Product Type: Small Molecule Compounds. CAS Number: 1001917-37-8. Molecular Weight: 471.53. Formula: C25H21N5O3S. UNSPSC Code: 12352200. Sorry - there are no images available for this product. Small Molecule Compounds from MedChem Express: HY-13299-1mL: MK-8033; HY-13299-5mg: MK-8033; HY-13299-10mg: MK ...

A Study of MK-8033 in Patients With Advanced Solid Tumors ...

This is a first-in-human trial to establish the safety, tolerability, Recommended Phase II Dose (RP2D), pharmacodynamic, and clinical activity of MK-8033. Parts A and B of the study will determine the maximum tolerated dose (MTD) and RP2D.

HQP8361 (MK-8033) - Product Profile - BCIQ

For the biopharma industry investment, business development and competitive intelligence professionals who require information to support financing, partnering and licensing activities, BCIQ provides accurate information and context to support profitable and strategic decision making. Unlike other intelligence solutions, BCIQ exclusively supports the unique needs of the biopharma industry and ...

MK-8033 | Semantic Scholar

MK-8033. Known as: MK8033, c-Met Inhibitor MK8033 An orally bioavailable inhibitor of c-Met, with potential antineoplastic activity. Upon administration, c-Met inhibitor MK8033 binds to and inhibits… Expand. National Institutes of Health Watch Topic ...

MK-8033 - Compound|Inhibitor|Targetmol

MK-8033 was orally dosed in GTL-16 tumor xenograft bearing mice. Mice were euthanized 1 h after dosing and tested for p-Met (Y1349) in tumors and MK-8033 concentrations in plasma. At 100 mg/kg, essentially complete inhibition of p-Met (Y1349) was achieved. An in vivo IC50 of 1.3 uM was deduced from the relationship between plasma MK-8033 level and Met pY1349. Dosing at 3, 10, 30, and 100 mg/kg ...

MK-8033 hydrochloride | c-Met/HGFR Inhibitor | MedChemExpress

MK-8033 potently inhibited GTL-16 proliferation with an IC50 of 582 ± 30 nM. By contrast the HCT116 cell line, which does not harbor basal c-Met activation, was not inhibited by MK-8033 (IC50 > 10000 nM) [1]. MK-8033 radiosensitized the high-c-Met-expressing EBC-1 and H1993 cells but not the low-c-Met-expressing cell lines A549 and H460. However, irradiation of A549 and H460 cells increased ...

DSPeaker AM 8033-MicAmp Mk. II Mess-Kit, Zubehör ...

Zubehör zum DSPeaker AM 8033 • MicAmp Mk. II Mess-Kit micampmessset Das MicAmp Mk. II Mess-Kit ermöglicht leicht durchführbare und be-zahlbare akustische Messungen mit profes-sioneller Genauigkeit. Bei der vorgeschlagenen An-wendung mit dem Präzisions-Messmikrofon des AM-8033 kann man sehr einfach die Raumantwort und somit die Klangverbesserung des Anti-Mode™ 8033 Subwoofer-Equalizers ...

Abstract #1751: MK-8033, a selective c-Met / Ron inhibitor ...

MK-8033 potently inhibits the kinase activity of c-Met (IC50 1.3 nM) and Ron (IC50 14 nM) while exhibiting no inhibitory activities against over 220 protein kinases when tested at 1\#956;M. The compound is a novel ATP-competitive inhibitor that is equally potent against wild type c-Met and naturally occurring oncogenic c-Met mutants, including activation loop mutants. MK-8033 inhibits both ...

AntiMode 8033 + MicAmp Mk. II Mess-Set, Lautsprecher ...

Das MicAmp Mk. II Mess-Set ermöglicht leicht durchführbare und bezahlbare akustische Messungen mit professioneller Genauigkeit. Bei der vorgeschlagenen Anwendung mit dem Präzisions-Messmikrofon des AM-8033 kann man sehr einfach die Raumantwort und somit die Klangverbesserung des Anti-Mode™ 8033 Subwoofer-Equalizers nachmessen und aufzeichnen.

APExBIO - MK-8033|C-MET inhibitor|CAS# 1001917-37-8

MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre- and post-treatment biopsies to evaluate for relevant molecular signatures.

MK-8033 | c-Met inhibitor | Buy MK-8033 from Supplier AdooQ®

MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.

First-in-human phase I dose escalation study of MK-8033 in ...

Background C-Met, which is frequently activated in multiple cancers, has been implicated in tumor formation, progression, metastasis, angiogenesis, and resistance to multiple therapies. MK-8033 is a small-molecule inhibitor of c-Met that binds …

Sony MKS-8033 Manuals

Sony MKS-8033 Pdf User Manuals. View online or download Sony MKS-8033 Operation Manual

MK-8033 (hydrochloride) • Focus Bioscience

MK8033 Hcl is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.

MK-8033 | c-Met Inhibitor | CSNpharm

MK-8033 Catalog No. CSN13613. MK-8033 is a specific dual ATP competitive c-MetRon inhibitor IC501 nM Wt c-Met under investigation as a treatment for cancer. Size Price Availability Quantity +1-708-781-1677. sales@csnpharm.com. tech@csnpharm.com. Add to Cart Bulk Inquiry. Add to My Favorites. Inquiry +1-708-781-1677 . sales@csnpharm.com. tech@csnpharm.com. Purity & Documentation Select Batch ...

MK-8033 Suppliers, Manufacturers & Traders at Chemsrc

Find here details of companies selling MK-8033, for your purchase requirements. Get latest info on MK-8033, suppliers, manufacturers, wholesalers, traders with MK-8033 prices for buying.

GC13140_MK-8033_1001917-37-8

"Protocol, Chemical Properties, Background of MK-8033. https://www.glpbio.com/mk-8033.html"

Bestellen - Anti-Mode Raumklangoptimierung mit Anti-Mode ...

Anti-Mode 8033 s-II, Euro 349; Anti-Mode 8033 cinema, Euro 289; Zubehör. MicAmp Mk. II Mess-Kit, Euro 65,00; Weiteres Zubehör & Kabel laut Liste; Summe. 0,00 € Kommentar oder Nachricht. Zahlung. Wir akzeptieren Bezahlung per Vorkasse (Banküberweisung/PayPal) Einkaufs- und Versandbedingungen von AK-Soundservices. Nach dem Absenden Ihrer Bestellung erhalten Sie von uns eine manuelle Mail ...

Anti-Mode 8033 S-II | Klangoptimierung | Audio/HiFi | GROBI.TV

Der Resonanzkiller 8033 S-II - Verbesserte Anti-Mode Korrektur durch 36 parametrische Filter - Zwei Korrekturfilter für Dipol Subwoofer - Fünf Lowpass (Cut-Off) Frequenzen zur Auswahl (60, 80, 100, 120, 140 Hz) - Frei zuschaltbares Subsonic Filter (10 Hz) - Linearisierbarer Frequenzumfang von 16 -250 Hz. Wer schon einmal während eines Filmes im Raum umhergelaufen ist, konnte bestimmt ...

MK-8033 | immune-source.com

MK-8033 Complicating diagnosis ovarian cancer has an incidence of just 12.6 per 100 0 women [2]. Therefore there is a pressing clinical need for a test that exhibits a high sensitivity for malignancies but also a high specificity to minimize the number of false positives that occur in such a low incidence disease. Clinically multiple lines of evidence are examined to assess the possibility of ...

MK-8033 supplier | CasNO.1001917-37-8

The MK-8033, with the CAS registry number 1001917-37-8, is also known as 3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-N-(2-pyridinylmethyl)-5H-benzo[4,5]cyclohepta[1,2-b]pyridine-7-methanesulfonamide. This chemical's molecular formula is C 25 H 21 N 5 O 3 S and molecular weight is 471.53. Physical properties of MK-8033 are: (1)ACD/LogP: 0.478; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.46 ...

MK-8033 | CAS:1001917-37-8 | C-MET inhibitor For Research ...

MK-8033(1001917-37-8) Reference standards for Pharmacological research. MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investig

8033, Elektronik gebraucht kaufen | eBay Kleinanzeigen

Verkaufe einen DSPeaker Anti-Mode 8033s-ll + DSPeaker MicAmp Mk.II - Messkit Neupreis 359€ +... 325 € 50259 Pulheim. 10.09.2019. DSPeaker Anti-Mode 8033 Cinema. Hallo, ich biete hier das AM 8033 Cinema. Wer das gefunden hat, weiß, denke ich worum es geht. Nur... 222 € VB 42655 Solingen. 09.09.2019. ITT Hifi 8033 Turner/Amplifier. Verstärker Knistert teilweise, daher vermutlich ...

C-Met Inhibitor MK-8003 Radiosensitizes c-Met–Expressing ...

MK-8033 radiosensitized the high-c-Met–expressing EBC-1 and H1993 cells but not the low-c-Met–expressing cell lines A549 and H460. However, irradiation of A549 and H460 cells increased the expression of c-Met protein at 30 minutes after the irradiation. Subsequent targeting of this up-regulated c-Met by using MK-8033 followed by a second radiation dose reduced the clonogenic survival of ...

MK-8033 | C-MET inhibitor | Cas# 1001917-37-8 - GlpBio

MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.IC50 Value: 1 nM (Wt c-Met); 2.0 nM (c-Met N1100Y) [1]Target: c-Met/Ronin vitro: MK-8033 binds 3-fold more tight

Selleck MK-8033

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MK-8033 |CAS:1001917-37-8 Probechem Biochemicals

MK-8033 |MK 8033;MK8033 |1001917-37-8 |MK-8033 is a potent, specific, dual c-Met/Ron kinases inhibitor with IC50 of 1/7 nM, also potently inhibits oncogenic c-Met activation loop mutants Y1230C, Y1230H and Y1235D with IC50 of 0.6-1.2 nM. |supplier |price |datasheet |IC50 |chemical structure |probechem inhibitor

A novel c-Met inhibitor, MK8033, synergizes with ...

Lee YJ, Kim DH, Lee SH, Kim DW, Nam HS and Cho MK: Expression of the c-Met proteins in malignant skin cancers. Ann Dermatol. 23:33–38. 2011. View Article: Google Scholar: PubMed/NCBI. 38 Syed ZA, Yin W, Hughes K, Gill JN, Shi R and Clifford JL: HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop ...

MK-8033 – Synthesis and Structure-activity Relationship of ...

Tag: MK-8033 Recent evidence shows that the introduction of Alzheimers disease (AD) and ...

CAS 1001917-37-8 MK-8033 - BOC Sciences

MK-8033 - CAS 1001917-37-8 Catalog number: 1001917-37-8 MK8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer. Please be kindly noted products are not for therapeutic use.

DSPeaker Anti-Mode 8033 DSP Subwoofer Equalizer (TAS 204 ...

The MK subwoofer as corrected by the Anti-Mode 8033 added to the Harbeths was considerably more precise and defined in the deep bottom end than either the (uncorrected) Harbeths alone or the uncorrected Harbeth/MK combination. The results with the Harbeth M40s plus subwoofer corrected by the AntiMode 8033 were spectacularly good. The orchestral ...

Discovery of 1-[3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-5H ...

This report documents the first example of a specific inhibitor of protein kinases with preferential binding to the activated kinase conformation: 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one 11r (MK-8033), a dual c-Met/Ron inhibitor under investigation as a treatment for cancer. The design of 11r was based on the desire to reduce time-dependent inhibition of CYP3A4 (TDI) by members of this ...

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Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

Audio-Technica AT 8033 – Musikhaus Thomann

Audio-Technica AT 8033, Kondensator Kleinmembranmikrofon speziell für Instrumenten und Sprachabnahme, 30 - 20.000 Hz, 250 Ohm, 137 dB SPL max., Batteriespeisung mit 1,5 Volt AA oder Phantomspeisung, Abmessungen: 194,2...

Steyr 1500 Funkkraftwagen - Conversation Set [Tamiya ...

Steyr 1500 Funkkraftwagen - Conversation Set [Tamiya] · Maßstab 1:48 · Hersteller: CMK · ArtNr. 8033 · Preis: 29.99 EUR online bestellen bei Modellbau-Universe, dem Modellbauversand im Internet

Dichtring Cu A33 x 39 x 2 für Ölstandsauge ...

für MK 80 Booster / Verdichter NK 200 / Pro9NK Weiterführende Links zu "Dichtring Cu A33 x 39 x 2 für Ölstandsauge" Fragen zum Artikel? Weitere Artikel von Renner Gmbh Kunden kauften auch Kunden haben sich ebenfalls angesehen. Kunden kauften auch. Dichtring	A26x32x1,5 SIV Einlass Thermostateinsatz	 O Ring 99 x 3,5 Viton, Sh90 Ölfilter Feinabscheidepatrone für MK 80 Ölstandsauge ...

So sieht die neue Regierung in Nord-Mazedonien aus ...

Der alte und neue Ministerpräsident von Nord-Mazedonien hat seine Regierung vorgestellt. Acht neue, sechs bisherige und fünf frühere Minister mit Erfahrungen aus unterschiedlichen Ressorts werden die neue Regierung in Nord-Makedonien unter Ministerpräsident Zoran Zaev bilden. Die Ministerien ...

BAL_8033 - HÖNNEZEITUNG - Aktuelle Nachrichten aus Balve ...

BAL_8033. Anzeige. Anzeige. Schreiben Sie einen Kommentar Antworten abbrechen. Deine E-Mail-Adresse wird nicht veröffentlicht. Erforderliche Felder sind mit * markiert. KOMMENTAR. Name * E-Mail * Website. Neueste Artikel. Falsche Polizei flüchtet vor Handy. 2 Stunden. BGS Eisborn lädt zum Sonntagsspaziergang ein – BM-Kandidat Schnadt ist dabei . 9 Stunden. Goldenes Ordensjubiläum. 10 ...

Люстра Arte Lamp A8033SP-3CC 8033


Подвесная люстра Arte Lamp производства Италия из коллекции 8033. В конструкции люстры A8033SP-3CC используются 3 плафона и металлическая арматура цвета хром. Габаритные размеры люстры 700x480 мм. Дизайн люстры отлично подходит для прихожей. Устанавливается на потолок.

9610 RUR
A8033SP-3CC 8033 Arte Lamp

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Люстра Arte Lamp A8033SP-3AB 8033


Подвесная люстра Arte Lamp производства Италия из коллекции 8033. В конструкции люстры A8033SP-3AB используются 3 плафона и металлическая арматура цвета бронза. Габаритные размеры люстры 700x480 мм. Дизайн люстры отлично подходит для прихожей. Устанавливается на потолок.

10130 RUR
A8033SP-3AB 8033 Arte Lamp

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Люстра Lussole LSP-8033 LSP-0541


Подвесная люстра Lussole производства Италия из коллекции LSP-0541. В конструкции люстры LSP-8033 используются 8 белых пластиковых плафонов конусной формы и металлическая арматура цвета белый. Габаритные размеры люстры 390x750 мм. Дизайн люстры отлично подходит для спальни. Устанавливается на потолок.

8522 RUR
LSP-8033 LSP-0541 Lussole

Lussole / LSP-8033 LSP-0541 / похожие

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Стильные кухни акции

Люстра Lussole GRLSP-8033 LSP-0541


Подвесная люстра Lussole производства Италия из коллекции LSP-0541. В конструкции люстры GRLSP-8033 используются 8 белых пластиковых плафонов конусной формы и металлическая арматура цвета белый. Габаритные размеры люстры 390x750 мм. Дизайн люстры отлично подходит для спальни. Устанавливается на потолок. В комплекте поставляются 8 ламп с цоколем E27.

9802 RUR
GRLSP-8033 LSP-0541 Lussole

Lussole / GRLSP-8033 LSP-0541 / похожие

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скипидарная мазь 25 г


745

35 RUR
Ярославская ФФ ЗАО

Ярославская ФФ ЗАО / / похожие

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Донный клапан с переливом Kaiser 8033

Ткань Португалия Ткани 8033 (50*70 см)


В набор входит: 1 отрез ткани. Размер: 50х70 см. Производитель: Португалия. Состав: пробка. Тип ткани: корк. Тип рисунка: однотонные. Цвет: бежевый. Тема орнамента: без узора.

1608 RUR
Ткани 8033 (50*70 см) Португалия

Португалия / Ткани 8033 (50*70 см) / похожие

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Шланговое подключение Paini 50CR480Q

Мясорубка Panasonic MK-ZJ3500


27788 RUR
MK-ZJ3500 Panasonic

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